When every second counts…
Instant Access to Overdose Medication
The CounterAct Cap is a novel nasal delivery system. The cap snaps directly on top of the prescription bottle and can contain rescue medication, such as Naloxone to be administered nasally in the event of an opioid overdose.
The CounterAct Cap is US patented
CounterAct is seeking drug development partners to advance this novel technology to save lives and mitigate the Opioid Overdose Epidemic.
People die each day from opioid-related drug overdose³
People misuse prescription opioids annually²
People died from opioid overdoses in 2020⁴
People had an opioid use disorder in 2019⁶
Economic Burden of prescription opioid misuse in the United States¹
Deaths attributed to overdose on commonly prescribed opioids in 2017²
Deaths attributed to overdose on synthetic opioids other than methadone in 2019⁵
Adolescents started to misuse prescription pain medications in 2017
A person is more likely to die from an accidental opioid overdose than from a motor vehicle crash.⁷
Re-Imagining Opioid Overdose Treatment
CounterAct has developed a US patented, Nasal Delivery Device that snaps on top of any bottle of prescription medicine. Underneath the outer cap is a nasal delivery system consisting of a stowed nasal nozzle that can be extended and inserted into a nostril in the event of an opioid overdose. With minimal pressure, the spring-loaded trigger can be pushed and the rescue medication can be nasally administered.
Health Human Services 5 Point Strategy to Combat the Opioid Overdose Epidemic
- Better Data by strengthening public health surveillance
- Better Pain Management
- Improving access to treatment, prevention and recovery services
- Increasing the availability of overdose-reversing drugs
- Supporting cutting-edge research

130 A Day And Growing: Answering The US Opioid Overdose Epidemic
In this article, Todd Pizitz, PhD, and Donald Mealing, both Co-Founders of CounterAct, discuss the ongoing opioid crisis in the US and the current use of the opioid reversal medication naxalone, and introduce the CounterAct device for naxalone home use. In the US in...
Breakthrough Opioid Overdose Nasal Spray Device Gets Closer to Reality
FDA Accepts CounterAct Proposal to Develop A New Opioid Overdose Spray Device that Fits Patient's Standard Opioid Prescription Pill Bottles. In September, 2018 CounterAct received a positive response from the United States Food and Drug Administration (FDA), enabling...
Help save lives: Co-prescribe naloxone to patients at risk of overdose
The nation’s opioid epidemic claimed more than 33,000 lives in 2015, but that figure would have been even higher if it wasn’t for the life-saving opioid overdose antidote naloxone. For more than 40 years, naloxone has been used to reverse the effects of opioid...
Surgeon General’s Advisory on Naloxone and Opioid Overdose
I, Surgeon General of the United States Public Health Service, VADM Jerome Adams, am emphasizing the importance of the overdose-reversing drug naloxone. For patients currently taking high doses of opioids as prescribed for pain, individuals misusing prescription...
Contact Us
Sources: 1 National Institute on Drug Abuse, 2 “economic burden” of prescription opioid misuse alone in the United States is $78.5 billion a year, including the costs of healthcare, lost productivity, addiction treatment, and criminal justice involvement.2, 2 hhs.gov, 3 A Time of Crisis for the Opioid Epidemic in the USA, volume 398, Issue 102977, p277., 4 Centers for Disease Control gov, 5 drugabuse.gov, 6 samhsa.gov, 7 4 National Safety Council, January 2019